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Types
of Lupus:
SLE
is a chronic autoimmune disease that is potentially debilitating and sometimes
fatal as the immune system attacks the body’s cell and tissue’s resulting
in inflammation and tissue damage. It
can affect any part of the body, but mostly harms the heart, joints, skin,
lungs, blood vessels, liver, kidneys and the nervous system. SLE is unpredictable with areas of flares alternating with
remission. Lupus can occur at any
age, and is most common in women. The
symptoms of lupus are treated since there is no known cure for it, SLE is
treated mainly with corticosteriods and immunosupressants.
Classification
Lupus
is a chronic autoimmune disease in which the body's own defense system attacks
otherwise healthy tissue. Clinically, it can affect multiple organ systems
including the heart, skin, joints, kidneys and nervous system. There are
several types of lupus; generally when the word 'lupus' alone is used, it
refers to the systemic lupus erythematosus or SLE as discussed in this
article. Other types include:
Lupus
being a chronic autoimmune disease where the body attacks it’s own defense
system on otherwise healthy tissue. It
can clinically attack multiple organs of the heart, skin, joints, kidneys and
nervous system. Lupus have several types which are Drug induced lupus, Lupus
nephritis, discoid lupus, subcutaneous lupus, and neonatal lupus being a rare
disease affecting babies born to women with SLE, sjogren’s syndrome or
sometimes no autoimmune disorder.
Epidemiology
Lupus
is a rare disease and has been seen to increase the awareness and education
since the early 1960’s. This can give patients accurate diagnosis helping
them estimate the people with lupus. 270,000
and 1.5 million people in the U.S have lupus making it more common then cystic
fibrosis or cerebral palsy. It
affects both females and males though it affects young women that are
diagnosed nine times more often then men.
SLE
can occur in anyone at any age, most commonly in women of childbearing age
affecting 1 in 4000 in the U.S. Women becoming afflicted far more often than
men the disease appears to be more prevalent in women of African, Asian,
Hispanic and Native American origin being due to socioeconomic factors.
People with relatives with SLE are at slightly higher risk than the
general population.
Many
people have theorized about Porphyrias and people that have lupus share very
similar symptoms including light sensitive, rashes, hair growth, stained
teeth.
features
of the disease, as well as advances in treatment.
Lupus
is divided into three historical periods that are classical, neoclassical, and
modern. Classical being when the
disease was first recognized, the neoclassical period was recognized in 1872
with the systemic manifestations of the disease and the modern period which
began 1948 with the discovery of the LE cell is characterized by the advances
in our knowledge of the pathophysiology and clinical laboratory features of
the disease and the advance treatment.
Medications
are useful for the disease were found in 1894 when quinine was reported to be
effective therapy. Later
salicylates in conjunction with quinine was noted to have a greater benefit.
Origins
of 'Lupus Erythematosus'
Lupus
is latin for wolf all explanations originate with the reddish,
butterfly-shaped malar rash that the disease classically exhibits across the
nose and cheeks.
1. In various accounts, some doctors thought the rash resembled the pattern of
fur on a wolf's face.
2. In other accounts doctors thought that the rash, which was often more
severe in earlier centuries, created lesions that resembled wolf bites or
scratches.
3. Stranger still is the account that the term "Lupus" didn't come
from Latin at all, but from the term for a French style of mask which women
reportedly wore to conceal the rash on their faces.
4. Another common explanation for the term is that the disease's course
involves repeated attacks like those of a voracious predator, leaving behind
the red blotches
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